DNA Repair Creme   28mL/0.9fl oz |  $52.00

DNA Repair Creme is part of the next generation (GEN IV) of technology to use enzymes and biotechnology to enhance your skin's recovery capabilities and to delay aging. These special enzymes that exist in nature, as well as in your body, are designed to repair damage to cellular DNA caused by exposure to solar radiation.

When your skin cells are exposed to large amounts of UV radiation, they undergo "Apoptosis" or cellular death; consequently, your DNA is damaged. Apoptosis causes sunburn, reduces the skin's ability to repair itself, and unleashes tissue-damaging, inflammatory mediators from the immune system. This weakening of the skin's defense mechanism is the main biological feature of the chronological and light-induced aging process.

To protect your cells from Apoptosis, the DNA repair enzymes in your body attach directly to the DNA molecules and repair damage. Although these enzymes are present in the human body, they are not found in great abundance. The GEN IV technology is based on this naturally occurring process.
The enzyme is extracted from a certain type of bacterium and algae that thrive in very UV-intense environments. Once extracted, enzymes are placed in a liposomal delivery system designed to penetrate your skin, enter your cells, and release the enzymes for use by your cells.
Clinical studies have shown that the enzymes can help repair damage to your DNA, prevent damage to the repair mechanisms of the skin and the formation of carcinogenic precursors, and delay aging. DNA Repair Creme does not prevent sunburn. We recommend that you use a sunblock.

Benefits:
+ Stimulates the natural recovery processes of your skin.
+ Promotes recovery from UV damage.
+ Enhances the skin's ability to recover from the effects of harmful agents.
+ Delays the aging process.
+ Uses enzymes and biotechnology.
+ Enzymes are encapsulated in liposomes.
+ Stimulates the natural defense mechanisms of your skin.

Recommended Use:
Apply a liberal amount evenly on entire face and neck. For best results use twice daily, morning and night.

Ingredients:
Purified Water, Santalum Album (Sandalwood) Wood Extract, Phellodendron Amurense Bark Extract, Hordeum Distichon (Barley) Extract, Behenyl Alcohol, Sodium Stearoyl Lactylate, Polyglyceryl-10 Pentastearate, Cyclomethicone, Dimethicone, Dipotassium Glycyrrhizate, Cetyl Esters, Glyceryl Stearate, Biosaccharide Gum-1, Cetearyl Alcohol, Phenoxyethanol, Micrococcus Lysate, Lecithin, Capric/Caprylic Triglyceride, Linoleic Acid, Glycine Soja (Soybean) Sterol, Phospholipids, Macadamia Ternifolia Seed Oil, Aleurites Moluccana Nut Oil, Hyaluronic Acid, Xanthan Gum, Propylparaben, Ethylparaben, Methylparaben, Butylparaben, Fragrance, Citric Acid.

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DNA REPAIR: The Key to Optimal Aging of the Skin & Body
By Vincent C. Giampapa, M.D., F.A.C.S.

We all notice and admire beautiful skin. The skin is the largest organ in the body and
because it is the most external extension of ourselves, it interacts with both the external
environment and the internal aging process. It is here that a good estimate of how someone
ages can be measured simply by the appearance of the skin itself.

The common connection between both general internal aging of the body and the external
aging of the skin can be directly related to DNA. It is the balance of DNA damage and
DNA repair that controls aging. Key cellular processes have been identified which are
directly related to aging. There have been recently clarified and documented on the
clinical level to markedly affect how both our skin and body ages. These processes include
genes that directly regulate 4 key essential reactions;
1) glycation—The cross linking of glucose and protein molecules, with harmful effects in terms of aging.
2) oxidation—Free radical damage to cells, with harmful results to genes, cell membranes and organelles.
3) methylation—The process whereby a methyl group attaches itself to a gene, rendering the gene inactive.
4) inflammation—The body’s response to infection and injury, normally a part of the
healing process. Chronic inflammation is one of the key components of the aging process.
A View of Skin Aging Cell membranes surrounding our skin cells are rich in polyunsaturated fatty acids 

and contain oxygen levels eight times higher than in the other portions of the cell. Free radicals, which
are produced in our body as a response to general cellular maintenance, cause damage to
the cell lipid membranes. This results in a release of inflammatory compounds around the
cell. Release of these inflammatory compounds in the cell membranes initiates a
cascade of events that results in activation of pro-inflammatory genes.

The most important factor that is activated by the above described events is the stimulation
of NF Kappa B and activator protein “AP1”. NFK-B and AP1 also play critical roles in the
regulation of collagen digesting enzymes. AP-1 turns on genes that express or activate
collagen digesting enzymes “collagenases” and “metalloproteinases”.
The control of NF Kappa B is the key molecular target for both aging of the skin and body.
Controlling NF Kappa B in relation to skin aging can be markedly improved by utilizing a
number of key compounds. Relevant research has documented six leading skin anti-aging agents:
1) Vitamin C Ester— “ascorbylpalmatate”
2) Lipoic Acid
3) DMAE-“dimethoaminoethanol”
4) Tocotrienols
5) Carboxy Alkyl Esters (CAE’s)-(AC-11)™ DNA Repair Compounds
The most recently discovered importance is carboxy alkyl esters (CAE’s), also known as,
“AC-11”. This compound is derived from a natural occurring herb in South America and
has been shown to be an extremely strong inhibitor of NFK -B. By inhibiting NFK- B,
the messages to the cells’ nucleus to produce these pro-inflammatory compounds and
collagen digestive enzymes are inhibited. A recently documented study by a major skin
company has shown that carboxy alkyl esters in the form of AC-11 cannot only augment
DNA repair at the skin level, but also inhibit and reverse damage induced by the sun.
Over the past 5 years, I have been utilizing the combination of these above mentioned
ingredients topically with a clinically positive effect on both the appearance and aging of skin.
During this time, a similar combination of internal anti-oxidants, which target and inhibit
NF Kappa B, have been used simultaneously as well. It is this combination of both oral
and topical antioxidants that results in the overall best clinical improvement in aging of the skin.
The oral supplement complex in combination with the topical cream preparations markedly
enhances collagen production, as well as, the intracellular hyalorinic acid levels needed
within the skin to hold all moistures and deliver cellular nutrients.
This preparation for the skin also contains a very dilute combination of estrogen, which has
been clinically shown to be one of the most effective ways of increasing collagen and
hyalorinic acid production. The combined use of both topical and oral
antioxidant compounds quite possibly will set a new standard for non-surgical treatments for
skin restoration. This approach forms the basis of a key anti-aging program that helps maintain
both the skin and the internal body in optimal health.

You can learn more about DNA Repair as the key to optimal aging in; The Anti-Aging
Solution: 5 Simple Steps to Looking and Feeling Young (Wiley & Sons) by Dr. Vincent
Giampapa, Ron Pero, Ph.D. and Marcia Zimmerman, C.N. and in The Basic
Principles and Practice of Anti-Aging Medicine & Age Management by Dr. Vincent
Giampapa or by visiting www.suracell.com or contact us via phone at: (973) 932-1200.

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